4-methoxy-2,5-dihydro-1H-pyrrol-2-one → 6-cyano-3,4-dihydro-2,2-dimethyl-trans-3-hydroxy-4-(4-methoxy-2-oxo-3-pyrrolin-1-yl)-2H-1-benzopyran
Reaktionsgleichung
[C:1]([C:3]1[CH:4]=[CH:5][C:6]2[O:11][C:10]([CH3:13])([CH3:12])[CH:9]3[O:14][CH:8]3[C:7]=2[CH:15]=1)#[N:2].[CH3:16][O:17][C:18]1[CH2:22][NH:21][C:20](=[O:23])[CH:19]=1.C(OC1CNC(=O)C=1)CCCCCCC>>[C:1]([C:3]1[CH:4]=[CH:5][C:6]2[O:11][C:10]([CH3:13])([CH3:12])[C@@H:9]([OH:14])[C@H:8]([N:21]3[CH2:22][C:18]([O:17][CH3:16])=[CH:19][C:20]3=[O:23])[C:7]=2[CH:15]=1)#[N:2]Komponenten
4
Versuchsvorschrift
Similarly, optionally replacing 6-cyano-3,4-dihydro-2,2-dimethyl-3,4-epoxy-2H-1-benzopyran with the appropriate compound of formula (2), and optionally replacing 4-methoxy-3-pyrrolin-2-one with the appropriate compound of formula (3), the following compounds of formula (I) are prepared:
Quellen und Nachweise
- ORD-Eintrag
- ord-4baf28b8fccf4c068d254fa140172645
- Quelldatensatz
- uspto-grants-1991_12
- Patentnummer
- US05072006
Notizen zur Reaktion
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