Ethyl orthoformate → 4,5-Dicyanoimidazole

HRID 1461495

Reaktionsgleichung

[NH2:1]/[C:2](/[C:7]#[N:8])=[C:3](\[NH2:6])/[C:4]#[N:5].[CH:9](OCC)(OCC)OCC>>[NH:6]1[C:3]([C:4]#[N:5])=[C:2]([C:7]#[N:8])[N:1]=[CH:9]1

Komponenten

Edukt 2

HCID 31214Ethyl orthoformate

HCID 2723951Diaminomaleonitrile

Produkt 1

HCID 707294,5-Dicyanoimidazole

Versuchsvorschrift

In another 5-step synthesis, diaminomaleonitrile can be reacted with triethyl orthoformate to give the imidazole-4,5-dinitrile which, after alkylation with dimethyl sulfate, hydrolysis and partial decarboxylation by heating in acetic anhydride, gives the compound of the formula Ia (R1 =CH3, X1 =COOH).

Quellen und Nachweise

ORD-Eintrag: ord-b806525abd5447d6919cda6d4c96f4d7
Quelldatensatz: uspto-grants-1991_12
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US05075452

Verknüpfte Notizen

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