Acetonitrile → Didodecyl P-[1-(N-Octadecyl-N-dodecyloxyamino)octadecyl]phosphonate

Beteiligte Stoffe

Reaktionsbedingungen

Reaktionsschritte

Following the procedure of Example 7, the title compound is prepared from 2.5 g (4.6 mmol) of N-(1-octadecylidene)-octadecylamine N-oxide, 2.9 g (5.0 mmol) of tri-n-dodecylphosphite, 3.0 g (10 mmol) of n-dodecyl iodide, 20 ml of acetonitrile and 40 ml of toluene by heating at 70° C. for 24 hours. The residue is purified by flash chromatography (10:1 hexane:ethyl acetate eluent) to give 1.5 g (29% yield) of the title compound as a white, low melting wax.

Herkunft & Nachweise