Piperidine → HCID 20454107, Verbindung

HRID 1462204Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1462204
[O:1]1[CH2:6][C:5](=S)[NH:4][C:3](=[O:8])[NH:2]1.[NH:9]1[CH2:14][CH2:13][CH2:12][CH2:11][CH2:10]1>O1CCOCC1>[N:9]1([C:5]2[CH2:6][O:1][NH:2][C:3](=[O:8])[N:4]=2)[CH2:14][CH2:13][CH2:12][CH2:11][CH2:10]1

Komponenten

4

Edukt 2

HCID 8082PiperidineHCID 30069082H-1,2,4-Oxadiazin-3(4H)-one, dihydro-5-thioxo-

Produkt 1

HCID 20454107HCID 20454107, VerbindungAusbeute 54 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 312751,4-DioxaneLösungsmittel

Versuchsvorschrift

To a solution of 0.7 g (0.005 mole) of 6H-1,2,4-oxadiazin-3(2H)-one-5(4H)-thione in 10 ml of dry freshly distilled dioxane is added 0.44 g (0.0052 mole) of piperidine. After stirring for 17 hours at room temperature, the solution is filtered, washed with chloroform and dried to give a yield of 0.49 g (54 percent) of 5-(1-piperidinyl)-6H-1,2,4-oxadiazin-3(2H)-one.

Aufarbeitung

  1. filtrationthe solution is filtered
  2. washwashed with chloroform
  3. customdried

Quellen und Nachweise

ORD-Eintrag
ord-e0888ee7576f44258efc6420c42c0acc
Quelldatensatz
uspto-grants-1984_07
Patentnummer
US04459403

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