4-Phenylpiperidine → 5-Bromo-1-methyl-2-[2-(4-phenylpiperidinyl)ethyl]-1H-naphth[1,2-d]imidazole
Reaktionsgleichung
Cl.[Br:2][C:3]1[C:19]2[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=2)[C:6]2[N:7]([CH3:13])[C:8]([CH2:10][CH2:11]Cl)=[N:9][C:5]=2[CH:4]=1.[C:20]1([CH:26]2[CH2:31][CH2:30][NH:29][CH2:28][CH2:27]2)[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1>>[Br:2][C:3]1[C:19]2[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=2)[C:6]2[N:7]([CH3:13])[C:8]([CH2:10][CH2:11][N:29]3[CH2:30][CH2:31][CH:26]([C:20]4[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=4)[CH2:27][CH2:28]3)=[N:9][C:5]=2[CH:4]=1Komponenten
3
Versuchsvorschrift
The compound of the title is prepared by condensing 5-bromo-2-(2-chloroethyl)-1-methyl-1H-naphth[1,2-d]imidazole hydrochloride with 4-phenylpiperidine according to the method described in the foregoing example. M.p. 182°-84° C.
Quellen und Nachweise
- ORD-Eintrag
- ord-95e2c7ae0bd34a5cb2baa7e41af805cf
- Quelldatensatz
- uspto-grants-1984_07