3-Oxo-4-aza-5-androstene-17beta-carboxylic acid → N-(1,1-Diphenylethyl)-3-oxo-4-azaandrost-5-ene-17beta-carboxamide

HRID 1463941

Reaktionsgleichung

Reaktionsgleichung von HRID 1463941
[O:1]=[C:2]1[CH2:19][CH2:18][C@@:17]2([CH3:20])[C:4](=[CH:5][CH2:6][C@@H:7]3[C@@H:16]2[CH2:15][CH2:14][C@@:12]2([CH3:13])[C@H:8]3[CH2:9][CH2:10][C@@H:11]2[C:21]([OH:23])=O)[NH:3]1.[C:24]1([C:30]([NH2:38])([C:32]2[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=2)[CH3:31])[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1>>[C:24]1([C:30]([NH:38][C:21]([C@H:11]2[CH2:10][CH2:9][C@H:8]3[C@H:7]4[C@H:16]([CH2:15][CH2:14][C@:12]23[CH3:13])[C@:17]2([CH3:20])[C:4]([NH:3][C:2](=[O:1])[CH2:19][CH2:18]2)=[CH:5][CH2:6]4)=[O:23])([C:32]2[CH:33]=[CH:34][CH:35]=[CH:36][CH:37]=2)[CH3:31])[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1

Komponenten

3

Edukt 2

HCID 4754473-Oxo-4-aza-5-androstene-17beta-carboxylic acidHCID 127611721,1-Diphenylethan-1-amine

Produkt 1

HCID 67750650N-(1,1-Diphenylethyl)-3-oxo-4-azaandrost-5-ene-17beta-carboxamideAusbeute 55 %

Versuchsvorschrift

The title compound was prepared in a yield of 55% in a similar manner to that described in Example 2 by reacting 3-oxo-4-azaandrost-5-ene-17β-carboxylic acid and 1,1-diphenylethylamine.

Quellen und Nachweise

ORD-Eintrag
ord-e80765d0f4254bacb74dec0c0a534abb
Quelldatensatz
uspto-grants-1994_04
Patentnummer
US05302621

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