3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline → HCID 68263104, Verbindung
Reaktionsgleichung
[NH2:1][C:2]1[C:3]2[S:10][CH:9]=[C:8]([C:11]([NH:13][C:14]3[CH:15]=[C:16]([CH:20]=[CH:21][C:22]=3[CH3:23])[C:17](O)=[O:18])=[O:12])[C:4]=2[N:5]=[CH:6][N:7]=1.[CH3:24][C:25]1[N:26]=[CH:27][N:28]([C:30]2[CH:31]=[C:32]([CH:34]=[C:35]([C:37]([F:40])([F:39])[F:38])[CH:36]=2)[NH2:33])[CH:29]=1>>[NH2:1][C:2]1[C:3]2[S:10][CH:9]=[C:8]([C:11]([NH:13][C:14]3[CH:15]=[C:16]([C:17](=[O:18])[NH:33][C:32]4[CH:34]=[C:35]([C:37]([F:38])([F:39])[F:40])[CH:36]=[C:30]([N:28]5[CH:29]=[C:25]([CH3:24])[N:26]=[CH:27]5)[CH:31]=4)[CH:20]=[CH:21][C:22]=3[CH3:23])=[O:12])[C:4]=2[N:5]=[CH:6][N:7]=1Komponenten
3
Versuchsvorschrift
The procedure of Step 5 of Example 1 was repeated except for using 3-(4-aminothieno[3,2-d]pyrimidine-7-carboxamido)-4-methylbenzoic acid obtained in Step 4 of Example 8 and 3-(4-methyl-1H-imidazole-1-yl)-5-(trifluoromethyl)aniline to obtain the title compound (see Table 1).
Quellen und Nachweise
- ORD-Eintrag
- ord-1d3db498123d44e3bfb7cdc78e054cd5
- Quelldatensatz
- uspto-grants-2015_04