Triphenylphosphine → [4-(Benzyloxy)benzyl](triphenyl)phosphonium chloride

HRID 1465482

Reaktionsgleichung

Reaktionsgleichung von HRID 1465482
[CH2:1]([O:8][C:9]1[CH:14]=[CH:13][C:12]([CH2:15][Cl:16])=[CH:11][CH:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:17]1([P:23]([C:30]2[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=2)[C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>C1(C)C=CC=CC=1>[Cl-:16].[CH2:1]([O:8][C:9]1[CH:14]=[CH:13][C:12]([CH2:15][P+:23]([C:24]2[CH:25]=[CH:26][CH:27]=[CH:28][CH:29]=2)([C:30]2[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=2)[C:17]2[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=2)=[CH:11][CH:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Komponenten

4

Edukt 2

HCID 11776TriphenylphosphineHCID 700424-Benzyloxybenzyl chloride

Produkt 1

HCID 383834[4-(Benzyloxy)benzyl](triphenyl)phosphonium chlorideAusbeute 88,1 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1140TolueneLösungsmittel

Versuchsvorschrift

To a suspension of 1-(benzyloxy)-4-(chloromethyl)benzene (4.890 g, 21.01 mmol) in toluene (25 ml) was added triphenylphosphine (6.617 g, 25.23 mmol). The mixture was heated under reflux for 24 hrs, and cooled to room temperature. The precipitate was collected by filtration, and dried under reduced pressure to give [4-(benzyloxy)benzyl](triphenyl)phosphonium chloride (9.166 g, yield 88.1%) as a white solid.

Aufarbeitung

  1. temperatureThe mixture was heated
  2. temperatureunder reflux for 24 hrs
  3. filtrationThe precipitate was collected by filtration
  4. customdried under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-813e6d3b514547329678200b2299595c
Quelldatensatz
uspto-grants-2015_04
Patentnummer
US08999989B2

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