Thionyl Chloride → 3-(chloromethyl)-1-methyl-1H-1,2,4-triazole hydrochloride
Reaktionsgleichung
[CH3:1][N:2]1[CH:6]=[N:5][C:4]([CH2:7]O)=[N:3]1.O=S(Cl)[Cl:11]>>[ClH:11].[Cl:11][CH2:7][C:4]1[N:5]=[CH:6][N:2]([CH3:1])[N:3]=1Komponenten
3
Versuchsvorschrift
(1-methyl-1H-1,2,4-triazol-3-yl)methanol (0.25 g, 2.2 mmol) was dissolved in 10 mL of SOCl2 and refluxed for 2 hours. The mixture was evaporated to dryness and coevaporated with toluene. The resulting white solid (0.2 g) was used in the next step without further purification.
Aufarbeitung
- temperaturerefluxed for 2 hours
- customThe mixture was evaporated to dryness
- customThe resulting white solid (0.2 g) was used in the next step without further purification
Quellen und Nachweise
- ORD-Eintrag
- ord-f8bbb8c4a75541d5942cb7421f31028e
- Quelldatensatz
- uspto-grants-2015_04
- Patentnummer
- US08999998B2
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