4-(2-Hydroxyethoxy)-3-methoxybenzoic acid → (S)-ethyl 4-amino-5-(2-(4-(2-hydroxyethoxy)-3-methoxybenzamido)butoxy)-2-methylquinoline-3-carboxylate

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	4-(2-Hydroxyethoxy)-3-methoxybenzoic acid	HCID 24694069	—
Edukt	(S)-ethyl 4-amino-5-(2-aminobutoxy)-2-methylquinoline-3-carboxylate	HCID 86658218	—
Produkt	(S)-ethyl 4-amino-5-(2-(4-(2-hydroxyethoxy)-3-methoxybenzamido)butoxy)-2-methylquinoline-3-carboxylate	HCID 86658220	—

Reaktionsschritte

Prepared as in Example 24a from (S)-ethyl 4-amino-5-(2-aminobutoxy)-2-methylquinoline-3-carboxylate (Example 97b) and 4-(2-hydroxyethoxy)-3-methoxybenzoic acid (Uto, Y. et al. Bioorg. Med. Chem. Lett. 2009, 19, 4151.) as brown solid (38%). MS 512 (MH+).

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US09000054B2
Quelldatensatz	uspto-grants-2015_04
ORD ID	ord-b76ab25913c4475584ba9be9c0d95259
Quellennotiz	uspto-grants-2015_04