5-(Methylsulfonyl)-1H-indole → trans(+/-)-tert-Butyl-3-fluoro-4-((6-(5-(methylsulfonyl)-1H-indol-1-yl)pyridin-3-yl)oxy)piperidine-1-carboxylate

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	5-(Methylsulfonyl)-1H-indole	HCID 14973230	—
Edukt	trans(+/-)-Tert-butyl-4-((6-chloropyridin-3-yl)oxy)-3-fluoropiperidine-1-carboxylate	HCID 131732699	—
Produkt	trans(+/-)-tert-Butyl-3-fluoro-4-((6-(5-(methylsulfonyl)-1H-indol-1-yl)pyridin-3-yl)oxy)piperidine-1-carboxylate	HCID 67807149	—

Reaktionsschritte

The title compound was prepared by following the similar procedure as described in Example-1 by using 5-(methylsulfonyl)-1H-indole (intermediate-21) and trans(±)-tert-butyl-4-((6-chloropyridin-3-yl)oxy)-3-fluoropiperidine-1-carboxylate (intermediate-63) (0.220 g, 37%).

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US09000175B2
Quelldatensatz	uspto-grants-2015_04
ORD ID	ord-8a75adf4647046bcac4ed8ea3ef395e2
Quellennotiz	uspto-grants-2015_04