Butaclamol → Dopamine

HRID 1468603

Reaktionsgleichung

Reaktionsgleichung von HRID 1468603
C[N:2]1[CH2:12][C@H:11](C2C=CC=CC=2)[C:10]2[CH:9]=[C:8]([OH:19])[C:7](Cl)=[CH:6][C:5]=2CC1.CC([C@]1([OH:47])C[C@H]2N(C[C@H]3C4C2=CC=CC=4CCC2C=CC=CC3=2)CC1)(C)C>>[NH2:2][CH2:12][CH2:11][C:10]1[CH:5]=[CH:6][C:7]([OH:47])=[C:8]([OH:19])[CH:9]=1

Komponenten

3

Edukt 2

HCID 37461ButaclamolHCID 3036864R-(+)-8-chloro-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1H-3-benzazepine-7-ol

Produkt 1

HCID 681Dopamine

Versuchsvorschrift

HEK cells were transfected with DNA encoding D1-NLS-GFP (2 micrograms), and D1-WT (6 micrograms) for 48 hours. These cells were treated 6 hrs after transfection with SCH-23390 (10 micromolar), or (+)butaclamol (10 micromolar). The medium containing antagonist was changed at 6, 22, 30 and 42 hours after transfection. Control cells received no antagonist treatment.

Aufarbeitung

  1. additionThe medium containing antagonist
  2. customwas changed at 6, 22, 30 and 42 hours

Quellen und Nachweise

ORD-Eintrag
ord-2d53400f0aa94749a7bcb6d4c13f86c7
Quelldatensatz
uspto-grants-2015_04
Patentnummer
US09005905B2

Verknüpfte Notizen

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