Piperidine → (1-Chloro-5-methylisoquinolin-4-yl)(piperidin-1-yl)methanone

HRID 1470464Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1470464
[Cl:1][C:2]1[C:11]2[C:6](=[C:7]([CH3:12])[CH:8]=[CH:9][CH:10]=2)[C:5]([C:13]([OH:15])=O)=[CH:4][N:3]=1.[NH:16]1[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17]1>>[Cl:1][C:2]1[C:11]2[C:6](=[C:7]([CH3:12])[CH:8]=[CH:9][CH:10]=2)[C:5]([C:13]([N:16]2[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17]2)=[O:15])=[CH:4][N:3]=1

Komponenten

3

Edukt 2

HCID 8082PiperidineHCID 84687221HCID 84687221, Verbindung

Produkt 1

HCID 86689580(1-Chloro-5-methylisoquinolin-4-yl)(piperidin-1-yl)methanone

Versuchsvorschrift

The title compound was prepared by using 1-chloro-5-methylisoquinolin-4-carboxylic acid (Intermediate-10) and piperidine by following the similar procedure as described for intermediate-11a.

Quellen und Nachweise

ORD-Eintrag
ord-800a51f1ea744a158844233cb4441def
Quelldatensatz
uspto-grants-2015_04
Patentnummer
US09006442B2

Notizen zur Reaktion

Wird geladen…