Pyrrolidine → (4-Methoxy-8-methylnaphthalen-1-yl)(pyrrolidin-1-yl)methanone
Reaktionsgleichung
[CH3:1][O:2][C:3]1[C:12]2[C:7](=[C:8]([CH3:13])[CH:9]=[CH:10][CH:11]=2)[C:6]([C:14]([OH:16])=O)=[CH:5][CH:4]=1.[NH:17]1[CH2:21][CH2:20][CH2:19][CH2:18]1>>[CH3:1][O:2][C:3]1[C:12]2[C:7](=[C:8]([CH3:13])[CH:9]=[CH:10][CH:11]=2)[C:6]([C:14]([N:17]2[CH2:21][CH2:20][CH2:19][CH2:18]2)=[O:16])=[CH:5][CH:4]=1Komponenten
3
Versuchsvorschrift
4-Methoxy-8-methyl-1-naphthoic acid (Step-5 of Intermediate-22) was reacted with pyrrolidine by following the similar procedure as described in Step-6 of Intermediate-22.
Quellen und Nachweise
- ORD-Eintrag
- ord-8d68ec4d5b5c452381250d9fbb9875b0
- Quelldatensatz
- uspto-grants-2015_04
- Patentnummer
- US09006442B2
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