HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Trifluoroacetic acid → 4-Benzyloxy-2-methoxyphenylacetic acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Trifluoroacetic acid | HCID 6422 | — |
| Edukt | Tert-butyl 2-(4-benzyloxy-2-methoxyphenyl)acetate | HCID 67304738 | — |
| Lösungsmittel | Dichloromethane | HCID 6344 | — |
| Produkt | 4-Benzyloxy-2-methoxyphenylacetic acid | HCID 11065571 | — |
Reaktionsschritte
A solution of tert-butyl [4-(benzyloxy)-2-methoxyphenyl]acetate (2.2 g, 6.70 mmol) in DCM (10 ml) was treated with TFA (10.3 ml, 134 mmol) and the mixture stirred at RT for 30 min. The volatiles were removed in vacuo to afford the title compound. LC/MS (m/z): 273 (M+H)+.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US09018224B2 |
| Quelldatensatz | uspto-grants-2015_04 |
| ORD ID | ord-b4e56eec541d44e08e7620453b45efec |
| Quellennotiz | uspto-grants-2015_04 |