Acetyl chloride → (Acetyloxy)-carbamic acid tert-butyl ester

HRID 1475960Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1475960
[C:1](Cl)(=[O:3])[CH3:2].[C:5]([O:9][C:10]([NH:12][OH:13])=[O:11])([CH3:8])([CH3:7])[CH3:6]>>[C:1]([O:13][NH:12][C:10]([O:9][C:5]([CH3:8])([CH3:7])[CH3:6])=[O:11])(=[O:3])[CH3:2]

Komponenten

3

Edukt 2

HCID 6367Acetyl chlorideHCID 97534tert-butyl N-hydroxycarbamate

Produkt 1

HCID 10058028(Acetyloxy)-carbamic acid tert-butyl ester

Versuchsvorschrift

[(tert-Butoxy)carbonyl]amino acetate is prepared from acetyl chloride and N-tert-butoxycarbonyl hydroxylamine according to Scheme 1 and the method described by Carpino et al. J. Am. Chem. Soc. 1959, 955-957. (10 g, 100%), 1H NMR (500 MHz, DMSO-d6) δ ppm 10.57 (1H, br. s.), 2.10 (3H, s), 1.41 (9H, s).

Quellen und Nachweise

ORD-Eintrag
ord-d05cb9b782534d2183f65ac043b75006
Quelldatensatz
uspto-grants-2015_04
Patentnummer
US09018411B2

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