HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 148Erstellt: 23. Oktober 2026
tert-Butyl carbamate → 2-(Tert-butoxycarbonylamino)-6-chloroisonicotinic acid
https://huagongshe.com/de/reaction/148
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|
| Edukt | tert-Butyl carbamate | HCID 77922 | — |
| Edukt | 2,6-Dichloroisonicotinic acid | HCID 94830 | — |
| Reagenz | Potassium Phosphate, Tribasic | HCID 62657 | — |
| Katalysator | 1,1'-(9,9-Dimethyl-9H-xanthene-4,5-diyl)bis(1,1-diphenylphosphine) | HCID 636044 | — |
| Katalysator | Bis(dibenzylideneacetone)palladium | HCID 9811564 | — |
| Lösungsmittel | 1,4-Dioxane | HCID 31275 | — |
| Produkt | 2-(Tert-butoxycarbonylamino)-6-chloroisonicotinic acid | HCID 72212052 | 0% |
Reaktionsschritte
Reagents were mixed in a 25 mL round bottom flask and flushed well with nitrogen - heated at 100 °C for 16 h. The mixture looked dark black. Could not detect any starting material or product! It was discarded.
Herkunft & Nachweise
| Quelldatensatz | 750 AstraZeneca ELN dataset |
|---|
| ORD ID | ord-7c9ead47a3324fac997f2b8af6afca02 |
|---|
| Quellennotiz | 750 AstraZeneca ELN dataset |
|---|
