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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1480045Erstellt: 25. Oktober 2026

2-Amino-2-methylpropionitrile → 5-Chloro-4-cyclopropylmethoxy-pyridine-2-carboxylic acid (cyano-dimethyl-methyl)-amide

https://huagongshe.com/reaction/1480045

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt2-Amino-2-methylpropionitrileHCID 88022—
Edukt5-Chloro-4-cyclopropylmethoxy-pyridine-2-carboxylic acidHCID 90203638—
Produkt5-Chloro-4-cyclopropylmethoxy-pyridine-2-carboxylic acid (cyano-dimethyl-methyl)-amideHCID 76282718—

Reaktionsschritte

The title compound was synthesized in analogy to Example 1, using 5-chloro-4-cyclopropylmethoxy-pyridine-2-carboxylic acid and 2-amino-2-methyl-propanenitrile (CAN 19355-69-2 as starting materials and isolated (50 mg, 78%) as colorless oil; LC-MS (UV peak area, m/z) 93.8%, 294.1001 (MH+).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS09409866B2
Quelldatensatzuspto-grants-2016_08
ORD IDord-116c0f1a1d25480890d20d308903682a
Quellennotizuspto-grants-2016_08