HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
(2R)-2-Amino-3,3-dimethylbutan-1-ol → 5-Chloro-4-cyclopropylmethoxy-pyridine-2-carboxylic acid ((R)-1-hydroxymethyl-2,2-dimethyl-propyl)-amide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | (2R)-2-Amino-3,3-dimethylbutan-1-ol | HCID 6932847 | — |
| Edukt | 5-Chloro-4-cyclopropylmethoxy-pyridine-2-carboxylic acid | HCID 90203638 | — |
| Produkt | 5-Chloro-4-cyclopropylmethoxy-pyridine-2-carboxylic acid ((R)-1-hydroxymethyl-2,2-dimethyl-propyl)-amide | HCID 76283444 | — |
Reaktionsschritte
The title compound was synthesized in analogy to Example 1, using 5-chloro-4-cyclopropylmethoxy-pyridine-2-carboxylic acid and (2R)-2-amino-3,3-dimethyl-1-butanol (CAN 112245-09-7) as starting materials and isolated (80 mg, 80%) as colorless oil; LC-MS (UV peak area, m/z) 100%, 327.1476 (MH+).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US09409866B2 |
| Quelldatensatz | uspto-grants-2016_08 |
| ORD ID | ord-00014752e5cd4091b6963e4de7d701a2 |
| Quellennotiz | uspto-grants-2016_08 |