HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3-(1,3-Thiazol-2-yl)oxetan-3-amine hydrochloride → 5-Cyclopropyl-4-cyclopropylmethoxy-pyridine-2-carboxylic acid (3-thiazol-2-yl-oxetan-3-yl)-amide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 3-(1,3-Thiazol-2-yl)oxetan-3-amine hydrochloride | HCID 86674782 | — |
| Edukt | 5-Cyclopropyl-4-cyclopropylmethoxy-pyridine-2-carboxylic acid | HCID 90203809 | — |
| Produkt | 5-Cyclopropyl-4-cyclopropylmethoxy-pyridine-2-carboxylic acid (3-thiazol-2-yl-oxetan-3-yl)-amide | HCID 76282969 | — |
Reaktionsschritte
The title compound was synthesized in analogy to Example 24d, using 5-Cyclopropyl-4-cyclopropylmethoxy-pyridine-2-carboxylic acid (Example 42c) and 3-(thiazol-2-yl)oxetan-3-amine hydrochloride (Example 32b) as starting materials and isolated (16 mg, 29%) as colorless oil; MS (ESI, m/z): 372.2 (M+H+).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US09409866B2 |
| Quelldatensatz | uspto-grants-2016_08 |
| ORD ID | ord-e3512e3c38644d31858506770f2857d6 |
| Quellennotiz | uspto-grants-2016_08 |