Ammonium Chloride → HCID 76281194, Verbindung
Reaktionsgleichung
[CH:1]1([C:4]2[C:5]([O:21][CH2:22][C:23]([F:26])([F:25])[F:24])=[CH:6][C:7]([C:10]([NH:12][CH:13]([C:17]([CH3:20])([CH3:19])[CH3:18])[C:14](O)=[O:15])=[O:11])=[N:8][CH:9]=2)[CH2:3][CH2:2]1.[Cl-].[NH4+:28]>>[NH2:28][C:14](=[O:15])[CH:13]([NH:12][C:10]([C:7]1[CH:6]=[C:5]([O:21][CH2:22][C:23]([F:25])([F:24])[F:26])[C:4]([CH:1]2[CH2:3][CH2:2]2)=[CH:9][N:8]=1)=[O:11])[C:17]([CH3:20])([CH3:19])[CH3:18]Komponenten
3
Versuchsvorschrift
The title compound was synthesized in analogy to Example 112e, using 2-[[5-cyclopropyl-4-(2,2,2-trifluoroethoxy)pyridine-2-carbonyl]amino]-3,3-dimethyl-butanoic acid (Example 194b) and ammonium chloride as starting materials and isolated (490 mg, 92%); MS (ESI, m/z): 374.5 (M+H+).
Aufarbeitung
- customisolated (490 mg, 92%)