2-Methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline → HCID 89996038, Verbindung

HRID 1480849

Reaktionsgleichung

Reaktionsgleichung von HRID 1480849
Br[C:2]1[CH:3]=[N:4][N:5]([CH3:9])[C:6]=1[CH2:7][OH:8].[CH3:10][O:11][C:12]1[CH:18]=[C:17](B2OC(C)(C)C(C)(C)O2)[CH:16]=[CH:15][C:13]=1[NH2:14]>>[NH2:14][C:13]1[CH:15]=[CH:16][C:17]([C:2]2[CH:3]=[N:4][N:5]([CH3:9])[C:6]=2[CH2:7][OH:8])=[CH:18][C:12]=1[O:11][CH3:10]

Komponenten

3

Edukt 2

HCID 177502072-Methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)anilineHCID 57415773(4-bromo-1-methyl-1H-pyrazol-5-yl)methanol

Produkt 1

HCID 89996038HCID 89996038, Verbindung

Versuchsvorschrift

The title compound was prepared according to the method described for Preparation 158 using (4-bromo-1-methyl-1H-pyrazol-5-yl)methanol (Preparation 222) and 2-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline. The residue was purified using Biotage silica gel column chromatography eluting with EtOAc followed by elution through an SCX-2 cartridge.

Aufarbeitung

  1. customThe residue was purified
  2. washeluting with EtOAc
  3. washfollowed by elution through an SCX-2 cartridge

Quellen und Nachweise

ORD-Eintrag
ord-bcb834331b3f43909113504e5aa25ee0
Quelldatensatz
uspto-grants-2016_08
Patentnummer
US09409907B2

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