6-Bromopyridine-2-carbaldehyde → 1-(6-Bromo-pyridin-2-ylmethyl)-piperidine-4-carboxylic acid cyclohexylamide

HRID 1486734Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1486734
[Br:1][C:2]1[N:7]=[C:6]([CH:8]=O)[CH:5]=[CH:4][CH:3]=1.Cl.[CH:11]1([NH:17][C:18]([CH:20]2[CH2:25][CH2:24][NH:23][CH2:22][CH2:21]2)=[O:19])[CH2:16][CH2:15][CH2:14][CH2:13][CH2:12]1>>[CH:11]1([NH:17][C:18]([CH:20]2[CH2:21][CH2:22][N:23]([CH2:8][C:6]3[CH:5]=[CH:4][CH:3]=[C:2]([Br:1])[N:7]=3)[CH2:24][CH2:25]2)=[O:19])[CH2:12][CH2:13][CH2:14][CH2:15][CH2:16]1

Komponenten

3

Edukt 2

HCID 27570096-Bromopyridine-2-carbaldehydeHCID 44630870N-cyclohexylpiperidine-4-carboxamide hydrochloride

Produkt 1

HCID 867065521-(6-Bromo-pyridin-2-ylmethyl)-piperidine-4-carboxylic acid cyclohexylamide

Versuchsvorschrift

The title compound is prepared according to the reaction 3.01c described above using 6-bromo-pyridine-2-carboxaldehyde and piperidine-4-carboxylic acid cyclohexylamide hydrochloride as in 3.01c: LC-MS A: tR=0.61 min; [M+H]+=382.20.

Quellen und Nachweise

ORD-Eintrag
ord-8028896ecee74d92892eb7de82998f2c
Quelldatensatz
uspto-grants-2016_08
Patentnummer
US09428456B2

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