HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1490558Erstellt: 27. Oktober 2026
Pentafluorobenzene → 4,4,5,5-Tetramethyl-2-(pentafluorophenyl)-1,3,2-dioxaborolane
https://huagongshe.com/reaction/1490558
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|
| Edukt | Pentafluorobenzene | HCID 9696 | — |
| Reagenz | Bis(pinacolato)diborane | HCID 2733548 | — |
| Reagenz | 3-pyridin-2-yl-2-(3-pyridin-2-yl-1H-1,3,2-benzodiazaborol-2-yl)-1H-1,3,2-benzodiazaborole | HCID 122380799 | — |
| Katalysator | Bis(1,5-cyclooctadiene)dimethoxydiiridium | HCID 76001521 | — |
| Lösungsmittel | Cyclopentyl methyl ether | HCID 138539 | — |
| Produkt | 4,4,5,5-Tetramethyl-2-(pentafluorophenyl)-1,3,2-dioxaborolane | HCID 23065713 | 87% |
Reaktionsschritte
The general procedure A was followed using 1,2,3,4,5-pentafluorobenzene (55.4 uL, 0.5 mmol) and B2pin2 (126.9 mg, 0.5 mmol, 1.0 eq.) as starting material. The resulting mixture was allowed to stir 16 hours at 100 oC. 5n was obtained as colorless oil (128.2 mg, 87%) after purification by silica gel flash chromatography (EtOAc/PE=1:10 v/v).
Herkunft & Nachweise
| DOI | 10.1021/jacs.5b05252 |
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| Quelldatensatz | Borylation dataset from Roche |
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| ORD ID | ord-54534f29ec2f4a67ac86529f28d9ea02 |
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| Quellennotiz | Borylation dataset from Roche |
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