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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 14907Erstellt: 23. Oktober 2026

Tert-Butylamine → tert-Butyl-[3-(2-chloro-pyrimidin-4-yl)-benzyl]-amine

https://huagongshe.com/de/reaction/14907

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktTert-ButylamineHCID 6385—
Edukt3-(2-Chloro-pyrimidin-4-yl)-benzaldehydeHCID 24901965—
Produkttert-Butyl-[3-(2-chloro-pyrimidin-4-yl)-benzyl]-amineHCID 8660331097%

Reaktionsschritte

3-(2-Chloro-pyrimidin-4-yl)-benzaldehyde (intermediate 1) and tert butylamine were coupled by procedure B. The yield was 97%. LC-MS showed the product had the expected M+H+ of 276. 1H NMR (Varian 300 MHz, CDCl3, shifts relative to the solvent peak at 7.24 ppm) 8.6 (d, 1H) 8.1 (s, 1H) 7.9 (d, 1H) 7.6 (d, 1H) 7.5 (m, 2H) 1.2 (s, 9H).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07732444B2
Quelldatensatzuspto-grants-2010_06
ORD IDord-4b4178151fca419dac819ae8ff154559
Quellennotizuspto-grants-2010_06