HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1491130Erstellt: 26. Oktober 2026
(Ethylthio)benzene → 2-(2-(Ethylthio)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
https://huagongshe.com/reaction/1491130
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|
| Edukt | (Ethylthio)benzene | HCID 12144 | — |
| Reagenz | Bis(pinacolato)diborane | HCID 2733548 | — |
| Reagenz | 2-Pyridin-2-yl-5-[2-[4-(trifluoromethyl)-1,3,2-dioxaborolan-2-yl]phenyl]pyridine | HCID 134956623 | — |
| Katalysator | Bis(1,5-cyclooctadiene)dimethoxydiiridium | HCID 76001521 | — |
| Lösungsmittel | P-Xylene | HCID 7809 | — |
| Produkt | 2-(2-(Ethylthio)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane | HCID 123787969 | 72% |
Reaktionsschritte
Ligand 3f: The mixture of product (95 mg, 72% yield, ortho/meta + para = >30); ortho-borylated product 4b was obtained by further purification of the crude mixture by GPC (89 mg, 67% yield), white solid (mp. 48-50 oC)
Herkunft & Nachweise
| DOI | 10.1002/anie.201610041 |
|---|
| Quelldatensatz | Borylation dataset from Roche |
|---|
| ORD ID | ord-b26c7059a55f4ed08e56318eb7eb563c |
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| Quellennotiz | Borylation dataset from Roche |
|---|
