HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1491142Erstellt: 26. Oktober 2026
N,N-Dimethyl-3-(methylsulfanyl)aniline → N,N-dimethyl-3-methylsulfanyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline
https://huagongshe.com/reaction/1491142
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|
| Edukt | N,N-Dimethyl-3-(methylsulfanyl)aniline | HCID 20403482 | — |
| Reagenz | Bis(pinacolato)diborane | HCID 2733548 | — |
| Reagenz | 2-Pyridin-2-yl-5-[2-[4-(trifluoromethyl)-1,3,2-dioxaborolan-2-yl]phenyl]pyridine | HCID 134956623 | — |
| Katalysator | Bis(1,5-cyclooctadiene)dimethoxydiiridium | HCID 76001521 | — |
| Lösungsmittel | P-Xylene | HCID 7809 | — |
| Produkt | N,N-dimethyl-3-methylsulfanyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline | HCID 132510266 | 76% |
Reaktionsschritte
Ligand 3f: A mixture of ortho- and meta-borylated products (111 mg, 76% yield, ortho/meta + para = >30); ortho-borylated product 4h was obtained by further purification by GPC (100 mg, 68% yield), yellow oil;
Herkunft & Nachweise
| DOI | 10.1002/anie.201610041 |
|---|
| Quelldatensatz | Borylation dataset from Roche |
|---|
| ORD ID | ord-1cb889e2f933486bac022f3a0a595351 |
|---|
| Quellennotiz | Borylation dataset from Roche |
|---|
