N-Methylethylenediamine → HCID 178480593, Verbindung

HRID 1492212Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1492212
I.CS[C:4](=[NH:18])[NH:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[N:12]1[CH2:17][CH2:16][O:15][CH2:14][CH2:13]1.[CH3:19][NH:20][CH2:21][CH2:22]N>C(O)C>[CH3:19][N:20]1[CH2:21][CH2:22][NH:18][C:4]1=[N:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[N:12]1[CH2:17][CH2:16][O:15][CH2:14][CH2:13]1

Komponenten

4

Edukt 2

HCID 8014N-MethylethylenediamineHCID 178503978HCID 178503978, Verbindung

Produkt 1

HCID 178480593HCID 178480593, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

A mixture of 2-methyl-1-(2-morpholinophenyl)-2-thiopseudourea hydroiodide (3 g prepared as described in Example 166), N-methylethylenediamine (2 ml) and absolute ethanol (35 ml) was heated under reflux for 8 hours to give a solid which was recrystallised from ethyl acetate to give 4-[2-(1-methyl-2-imidazolidinylideneamino)phenyl]morpholine (m.p. 156° C.).

Aufarbeitung

  1. temperaturewas heated
  2. temperatureunder reflux for 8 hours
  3. customto give a solid which
  4. customwas recrystallised from ethyl acetate

Quellen und Nachweise

ORD-Eintrag
ord-b68e31d5b70d4bf4b5a35ed6481e2e7f
Quelldatensatz
uspto-grants-1994_12
Patentnummer
US05373008

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