Phthalic Anhydride → HCID 16654924, Verbindung

HRID 1492922Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1492922
[C:1]1(=[O:11])[O:6][C:4](=O)[C:3]2=[CH:7][CH:8]=[CH:9][CH:10]=[C:2]12.Cl.[Cl:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][NH2:19].C(N(CC)CC)C>C1(C)C=CC=CC=1>[Cl:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][N:19]1[C:1](=[O:11])[C:2]2=[CH:10][CH:9]=[CH:8][CH:7]=[C:3]2[C:4]1=[O:6]

Komponenten

5

Edukt 3

HCID 6811Phthalic AnhydrideHCID 8471TriethylamineHCID 189498945-Chloropentan-1-aminato(4-)--hydrogen chlorido(4-) (1/1)

Produkt 1

HCID 16654924HCID 16654924, VerbindungAusbeute 72,5 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1140TolueneLösungsmittel

Versuchsvorschrift

A solution of 20.6 g (0.139 mole) of phthalic anhydride, 20 g (0.126 mole) of 5-chloropentylamine hydrochloride and 17.6 ml (0.126 mole) of triethylamine in 250 ml of toluene was heated to 130° C. for 4 hours. The obtained mixture was evaporated to dryness. The residue was taken up into 200 ml of water and extracted with ethyl acetate. The phases were separated and the organic phase was dried over sodium sulfate and evaporated to dryness. From the crude product, 23 g of the title product were obtained as an oil having the following characteristics:

Aufarbeitung

  1. customThe obtained mixture was evaporated to dryness
  2. extractionextracted with ethyl acetate
  3. customThe phases were separated
  4. dry with materialthe organic phase was dried over sodium sulfate
  5. customevaporated to dryness

Quellen und Nachweise

ORD-Eintrag
ord-8116affbaa734cef96d8a0e07d2b2bf2
Quelldatensatz
uspto-grants-1994_12
Patentnummer
US05376673

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