Hydrochloric Acid → N-[4-(4-t-butylphenoxy)-3-aminophenyl]methane sulphonamide

Beteiligte Stoffe

Reaktionsschritte

N-(4-chloro-3-nitrophenyl)methanesulphonamide (50 g, 0.2 mole), 4-t-butylphenol (33 g, 0.22 mole), potassium carbonate (62.1 g, 0.45 mole) and diglyme (50 ml) were heated and stirred at 165°-170° for 24 hr. The mixture was cooled to 110° and xylene (150 ml) followed by a mixture of 10M-hydrochloric acid (55 ml) and water (130 ml) added.

Herkunft & Nachweise