Butylamine → 4-Butylamino-1-cyclohexyloxy-2,2,6,6-tetramethylpiperidine

Beteiligte Stoffe

Reaktionsschritte

A mixture of 9.5 grams (37.5 mmol) of 1-cyclohexyloxy-2, 2,6,6-tetramethylpiperidin-4-one, 13.7 grams (187 mmol) of n-butylamine, 0.4 gram of platinum oxide, and 120 ml of ethanol is hydrogenated on a Parr apparatus (50 psi, ambient temperature) till hydrogen uptake ceases. The catalyst is removed by filtration and the filtrate is evaporated to afford 10.8 grams (93% yield) of the title compound as a colorless syrup.

Herkunft & Nachweise