Methyl bromoacetate → HCID 15166966, Verbindung

Reaktionsgleichung

[Cl:1][C:2]1[CH:11]=[C:10]2[C:5]([C:6]([OH:16])=[CH:7][C:8]([C:12]([O:14][CH3:15])=[O:13])=[N:9]2)=[CH:4][CH:3]=1.Br[CH2:18][C:19]([O:21][CH3:22])=[O:20]>>[Cl:1][C:2]1[CH:11]=[C:10]2[C:5]([C:6]([O:16][CH2:18][C:19]([O:21][CH3:22])=[O:20])=[CH:7][C:8]([C:12]([O:14][CH3:15])=[O:13])=[N:9]2)=[CH:4][CH:3]=1

Komponenten

Edukt 2

HCID 60984Methyl bromoacetate

HCID 178498504HCID 178498504, Verbindung

Produkt 1

HCID 15166966HCID 15166966, Verbindung

Versuchsvorschrift

The purified methyl 7-chloro-4-hydroxy-2-quinolinecarboxylate was alkylated with methyl bromoacetate as described in example 2 to produce methyl 7-chloro-4- methoxycarbonylmethyloxy-2-quinolinecarboxylate as a white solid having a melting point of 153.5°-154.5° C.

Quellen und Nachweise

ORD-Eintrag: ord-75ea8723b3e14f409d23e29b273ef838
Quelldatensatz: uspto-grants-1991_06
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US05026700

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