Ethanolamine → HC Yellow no. 12

HRID 1494353Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1494353
Cl[C:2]1[CH:7]=[CH:6][C:5]([Cl:8])=[CH:4][C:3]=1[N+:9]([O-:11])=[O:10].[CH2:12]([CH2:14][NH2:15])[OH:13]>C(O)CCC>[OH:13][CH2:12][CH2:14][NH:15][C:2]1[CH:7]=[CH:6][C:5]([Cl:8])=[CH:4][C:3]=1[N+:9]([O-:11])=[O:10]

Komponenten

4

Edukt 2

HCID 700EthanolamineHCID 69772,5-Dichloronitrobenzene

Produkt 1

HCID 5182864HC Yellow no. 12Ausbeute 75 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 2631-ButanolLösungsmittel

Versuchsvorschrift

To a solution of 10 g (52 mmol) 2,5-dichloronitrobenzene in 40 ml butanol was added 6.5 g (104 mmol) ethanolamine, and the mixture was refluxed for 20 h. The reaction mixture was evaporated in vacuo. The residue was recrystallized (toluene) to give 8.1 g (75%) N-(2-hydroxyethyl)-4-chloro-2-nitroaniline. M.p. 98°-100° C.

Aufarbeitung

  1. temperaturethe mixture was refluxed for 20 h
  2. customThe reaction mixture was evaporated in vacuo
  3. customThe residue was recrystallized (toluene)

Quellen und Nachweise

ORD-Eintrag
ord-1a2fd3ed3b8c44cabddfd871c438b13f
Quelldatensatz
uspto-grants-1991_06
Patentnummer
US05026704

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