HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Potassium Carbonate → 1-(4-(3-Ethoxy-4-nitrophenyl)piperazin-1-yl)ethanone
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Potassium Carbonate | HCID 11430 | — |
| Edukt | 1-Acetylpiperazine | HCID 83795 | — |
| Edukt | 2-Ethoxy-4-fluoronitrobenzene | HCID 12918153 | — |
| Lösungsmittel | Dimethylformamide | HCID 6228 | — |
| Produkt | 1-(4-(3-Ethoxy-4-nitrophenyl)piperazin-1-yl)ethanone | HCID 118105754 | — |
Reaktionsschritte
The compound obtained in Step 1 above (300 mg), N-acetylpiperazine (300 mg), and potassium carbonate (500 mg) were dissolved in dimethylformamide (3 mL) and reacted at 80° C. overnight. The dimethylformamide of the reaction mixture was removed under reduced pressure, and added with water to form a solid. The solid was filtered to obtain a target compound as a yellow solid.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US09199944B2 |
| Quelldatensatz | uspto-grants-2015_12 |
| ORD ID | ord-2c8e1a83285440b6b1edfc06111e3ca8 |
| Quellennotiz | uspto-grants-2015_12 |