2,3-Diaminobenzoic acid methyl ester → Methyl 2-(2-ethoxy-2-oxoethyl)-1H-benzimidazole-4-carboxylate

Beteiligte Stoffe

Reaktionsschritte

A solution of methyl 2,3-diaminobenzoate (680 mg) and ethyl 3-amino-3-ethoxyacrylate hydrochloride (880 mg) in EtOH (12 mL) was stirred at 60° C. for 2 hours. EtOH was removed under reduced pressure, and the residue was purified on column chromatography to obtain the titled compound (1.14 g) as a pale yellow solid.

Herkunft & Nachweise