m-Chloroperbenzoic acid → HCID 178526232, Verbindung
Reaktionsgleichung
ClC1C=CC=C(C(OO)=[O:9])C=1.[Br:12][C:13]1[CH:14]=[C:15]2[N:21]=[CH:20][NH:19][C:16]2=[N:17][CH:18]=1>C(OCC)(=O)C>[Br:12][C:13]1[CH:14]=[C:15]2[N:21]=[CH:20][NH:19][C:16]2=[N+:17]([O-:9])[CH:18]=1Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
m-Chloroperbenzoic acid (25 wt % water content, 2.77 g, 12.0 mmol) was gradually added dropwise to 6-bromo-3H-imidazo[4,5-b]pyridine (1.58 mg, 7.98 mmol) in ethyl acetate (15 mL), and the reaction mixture was stirred at room temperature for one day. The precipitated solid was collected by filtration and washed with ethyl acetate and diethyl ether and dried under reduced pressure to give the title compound as a pale yellow solid (1.67 g, yield 98%).
Aufarbeitung
- filtrationThe precipitated solid was collected by filtration
- washwashed with ethyl acetate and diethyl ether
- customdried under reduced pressure
Quellen und Nachweise
- ORD-Eintrag
- ord-86d93005289b43f39430e39ef5af3d7b
- Quelldatensatz
- uspto-grants-2015_12
- Patentnummer
- US09216999B2
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