HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-Aza-6,9-dichloro-2-methoxyacridine → 7-Chloro-2-methoxy-N-(2-(4-methylpiperazin-1-yl)ethyl)benzo[b][1,5]naphthyridin-10-amine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-Aza-6,9-dichloro-2-methoxyacridine | HCID 23107 | — |
| Edukt | 4-Methylpiperazine-1-ethylamine | HCID 70284 | — |
| Produkt | 7-Chloro-2-methoxy-N-(2-(4-methylpiperazin-1-yl)ethyl)benzo[b][1,5]naphthyridin-10-amine | HCID 71006631 | — |
Reaktionsschritte
Following the general procedure of Example 1 and making non-critical variations but using 7,10-dichloro-2-methoxypyrido[3,2-b]quinoline and 2-(4-methylpiperazin-1-yl)ethanamine, the title compound was obtained; MS (Found M+1=386). 1H NMR (DMSO-d6, 400 Hz): 8.43-8.41 (d, 1H, J=9.2 Hz), 8.12-8.10 (d, 1H, J=9.2 Hz), 7.87 (b, 1H), 7.2 (s, 1H), 7.2.9-7.27 (d, 1H, J=9.2 Hz) 7.25-7.24 (d, 1H, J=9.2 Hz), 4.10 (m, 2H), 4.06 (s, 3H), 2.70-2.68 (m, 2H), 2.33 (b, 8H), 2.14 (s, 3H).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US09221760B2 |
| Quelldatensatz | uspto-grants-2015_12 |
| ORD ID | ord-06680b69475d4b2ba4696a09cbd34eba |
| Quellennotiz | uspto-grants-2015_12 |