2-(2-Benzoxazolyl)phenol → HCID 67072674, Verbindung

HRID 1506817

Reaktionsgleichung

Reaktionsgleichung von HRID 1506817
C1(B([O:14][B:15]([C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)[C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)C2C=CC=CC=2)C=CC=CC=1.O[C:29]1[CH:34]=[CH:33][CH:32]=[CH:31][C:30]=1[C:35]1[O:36][C:37]2[CH:43]=[CH:42][CH:41]=[CH:40][C:38]=2[N:39]=1>O1CCCC1>[C:22]1([B:15]([C:16]2[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=2)[O:14][C:29]2[CH:34]=[CH:33][CH:32]=[CH:31][C:30]=2[C:35]2[O:36][C:37]3[CH:43]=[CH:42][CH:41]=[CH:40][C:38]=3[N:39]=2)[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=1

Komponenten

4

Edukt 2

HCID 132692-(2-Benzoxazolyl)phenolHCID 596810Diphenylborinic anhydride

Produkt 1

HCID 67072674HCID 67072674, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 8028TetrahydrofuranLösungsmittel2×

Versuchsvorschrift

A solution of diphenylborinic anhydride (5.0 g; 0.014 mole) in tetrahydrofuran (20 ml) was added to a solution of 2-(2′-hydroxyphenyl)benzoxazole (3.1 g; 0.014 mole) in tetrahydrofuran (10 ml). The reaction mixture was refluxed under nitrogen for 2 h and allowed to cool to room temperature, then kept in the refrigerator for 18 h. The product was filtered off under suction, washed with methanol and dried under vacuum at 80° C. for 6 h. Yield 4.4 g (84%). The product was further purified by sublimation (85%). M.p 195° C. (DSC, onset); Tg 59° C. Elemental analysis:

Aufarbeitung

  1. temperatureThe reaction mixture was refluxed under nitrogen for 2 h
  2. filtrationThe product was filtered off under suction
  3. washwashed with methanol
  4. customdried under vacuum at 80° C. for 6 h
  5. customThe product was further purified by sublimation (85%)
  6. customM.p 195° C. (DSC, onset)

Quellen und Nachweise

ORD-Eintrag
ord-0c15ac0549a74bb9b8ae73caa55a46a3
Quelldatensatz
uspto-grants-2015_12
Patentnummer
US09221770B2

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