Cyanamide → HCID 178512257, Verbindung

HRID 1508700Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1508700
[Cl:1][C:2]1[S:6][C:5]([C:7]#[N:8])=[CH:4][CH:3]=1.O(C)[Na].[NH2:12][C:13]#N.[NH4+:15].[Cl-]>CO>[Cl:1][C:2]1[S:6][C:5]([C:7](=[NH:15])[NH:8][C:13]#[N:12])=[CH:4][CH:3]=1

Komponenten

6

Edukt 4

HCID 9864CyanamideHCID 25517Ammonium ChlorideHCID 122032655-Chloro-2-thiophenecarbonitrileHCID 178418582HCID 178418582, Verbindung

Produkt 1

HCID 178512257HCID 178512257, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 887MethanolLösungsmittel

Versuchsvorschrift

To a solution of 5-chlorothiophene-2-carbonitrile 1 in MeOH was added NaOCH3. The reaction mixture was stirred at room temperature for 4 h and then NH2CN was added. The reaction was allowed stir for overnight under N2. The mixture was then poured into NH4Cl (aq) and the precipitate collected and washed with water. The dried sample was confirmed as desired product 5-chloro-N-cyanothiophene-2-carboximidamide 2.

Aufarbeitung

  1. stirringThe reaction was allowed stir for overnight under N2
  2. customthe precipitate collected
  3. washwashed with water

Quellen und Nachweise

ORD-Eintrag
ord-2b2e2c1a069d4abc9fd26b833e6bcf8c
Quelldatensatz
uspto-grants-2015_12
Patentnummer
US09221843B2

Notizen zur Reaktion

Wird geladen…