Sodium Hydroxide → HCID 61834499, Verbindung

Reaktionsgleichung

[CH3:1][C:2]1[CH:3]=[C:4]([NH:16]C(=O)C)[CH:5]=[CH:6][C:7]=1[C:8]([N:10]1[CH2:15][CH2:14][O:13][CH2:12][CH2:11]1)=[O:9].[OH-].[Na+]>>[CH3:1][C:2]1[CH:3]=[C:4]([CH:5]=[CH:6][C:7]=1[C:8]([N:10]1[CH2:15][CH2:14][O:13][CH2:12][CH2:11]1)=[O:9])[NH2:16]

Komponenten

Edukt 2

HCID 14798Sodium Hydroxide

HCID 68637681N-[3-methyl-4-(morpholin-4-yl-carbonyl)-phenyl]-acetamide

Produkt 1

HCID 61834499HCID 61834499, Verbindung

Reaktionsbedingungen

Temperatur: 65 °C

Versuchsvorschrift

700.0 mg (2.67 mmol) N-[3-methyl-4-(morpholin-4-yl-carbonyl)-phenyl]-acetamide are combined with 7 ml 4-molar sodium hydroxide solution and stirred overnight at 65° C. The reaction mixture is poured onto ice water and extracted with ethyl acetate. The organic phase is dried over magnesium sulphate and evaporated down i. vac.

Aufarbeitung

additionThe reaction mixture is poured onto ice water
extractionextracted with ethyl acetate
dry with materialThe organic phase is dried over magnesium sulphate
customevaporated down i

Quellen und Nachweise

ORD-Eintrag: ord-0aa6374f81f648318495f33d600113bb
Quelldatensatz: uspto-grants-2010_06
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US07732466B2

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