Ethyl formate → HCID 86639223, Verbindung
Reaktionsgleichung
[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH2:6][NH:7][CH2:8][CH2:9][C:10]([O:12][CH2:13][CH3:14])=[O:11].[CH:15](OCC)=[O:16]>C1(C)C=CC=CC=1>[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH2:6][N:7]([CH:15]=[O:16])[CH2:8][CH2:9][C:10]([O:12][CH2:13][CH3:14])=[O:11]Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
Ethyl 3-[(thiophen-2-ylmethyl)amino]propionate (13.8 g) prepared in the step 1 and 47.8 g of ethyl formate were dissolved in 100 mL of toluene and heated to reflux overnight. After the reaction solution was cooled, the solvent was evaporated therefrom in vacuo to give 15.6 g of the objective compound as light yellow liquid.
Aufarbeitung
- temperatureheated
- temperatureto reflux overnight
- temperatureAfter the reaction solution was cooled
- customthe solvent was evaporated
Quellen und Nachweise
- ORD-Eintrag
- ord-bc2babd608984d479558c4097b7a0a7d
- Quelldatensatz
- uspto-grants-2012_07
- Patentnummer
- US08217031B2
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