1,2-Dichloro-4-fluorobenzene → 7-(3,4-Dichlorophenyloxy)-4,5,6,7-tetrahydrofuro[3,2-c]pyridine
Reaktionsgleichung
[O:1]1[C:9]2[CH:8]([OH:10])[CH2:7][NH:6][CH2:5][C:4]=2[CH:3]=[CH:2]1.[Cl:11][C:12]1[CH:13]=[C:14](F)[CH:15]=[CH:16][C:17]=1[Cl:18]>>[Cl:11][C:12]1[CH:13]=[C:14]([O:10][CH:8]2[CH2:7][NH:6][CH2:5][C:4]3[CH:3]=[CH:2][O:1][C:9]2=3)[CH:15]=[CH:16][C:17]=1[Cl:18]Komponenten
3
Versuchsvorschrift
The same method as in Example 1 was conducted using 4,5,6,7-tetrahydrofuro[3,2-c]pyridin-7-ol (Reference Example 33) instead of 6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-4-ol (Reference Example 6) and was conducted using 3,4-dichloro-1-fluorobenzene instead of 1-fluoronaphthalene to give the objective compound.
Aufarbeitung
- customto give the objective compound
Quellen und Nachweise
- ORD-Eintrag
- ord-48f9cfdb447a43ce839362dd294e24fa