HCID 44549262, Verbindung → HCID 53404692, Verbindung

HRID 1512980Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1512980
[CH3:1][C:2]1[C:7]([N+:8]([O-])=O)=[CH:6][N:5]=[C:4]([C:11]([O:13][CH2:14][CH3:15])=[O:12])[CH:3]=1>C(O)C.[C].[Pd]>[NH2:8][C:7]1[C:2]([CH3:1])=[CH:3][C:4]([C:11]([O:13][CH2:14][CH3:15])=[O:12])=[N:5][CH:6]=1

Komponenten

4

Edukt 1

HCID 44549262HCID 44549262, Verbindung

Produkt 1

HCID 53404692HCID 53404692, VerbindungAusbeute 98,9 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 178418390HCID 178418390, VerbindungKatalysatorHCID 702EthanolLösungsmittel

Versuchsvorschrift

A mixture of ethyl 4-methyl-5-nitropyridine-2-carboxylate (3.23 g) and 10% palladium-carbon powder (0.65 g) in ethanol (50 mL) was stirred at room temperature under a hydrogen atmosphere overnight. The insoluble material was removed by filtration, and the filtrate was concentrated under reduced pressure to give the title compound (2.74 g).

Aufarbeitung

  1. customThe insoluble material was removed by filtration
  2. concentrationthe filtrate was concentrated under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-affccc2327f74309bef80e98dd2f71e6
Quelldatensatz
uspto-grants-2012_07
Patentnummer
US08217069B2

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