Iodine → 1-Ethylsulfanylsulfonyl-4-methylbenzene

HRID 1515125

Reaktionsgleichung

Reaktionsgleichung von HRID 1515125
[CH2:1]([S:3]SCC)[CH3:2].[C:7]1([CH3:16])[CH:12]=[CH:11][C:10]([S:13]([O-:15])=[O:14])=[CH:9][CH:8]=1.[Na+].II>>[C:7]1([CH3:16])[CH:12]=[CH:11][C:10]([S:13](=[O:15])([S:3][CH2:1][CH3:2])=[O:14])=[CH:9][CH:8]=1

Komponenten

4

Edukt 3

HCID 807IodineHCID 8077Diethyl disulfideHCID 2723791Sodium p-toluenesulfinate

Produkt 1

HCID 4800411-Ethylsulfanylsulfonyl-4-methylbenzeneAusbeute 100 %

Versuchsvorschrift

The reaction was carried out using 0.60 mL (4.87 mmoL) of diethyl disulfide, 2.78 g (15.6 mmoL) of sodium p-toluenesulfinate, 2.47 g (9.74 mmoL) of iodine in accordance with the method of Reference Example 3, and the obtained residue was purified by silica gel column chromatography (hexane:ethyl acetate=8:1) to obtain 2.11 g of the heading compound as a colorless oily substance (yield 100%).

Aufarbeitung

  1. customthe obtained residue was purified by silica gel column chromatography (hexane:ethyl acetate=8:1)

Quellen und Nachweise

ORD-Eintrag
ord-e4712a18d0d144cbaaf6ae12dbb30cd8
Quelldatensatz
uspto-grants-2012_07
Patentnummer
US08222407B2

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