Acetyl hypofluorite → 2-Acetoxy-4-methylpyridine
Reaktionsgleichung
[OH:1][C:2]1[CH:7]=[C:6]([CH3:8])[CH:5]=[CH:4][N:3]=1.F[O:10][C:11](=O)[CH3:12]>>[C:11]([O:1][C:2]1[CH:7]=[C:6]([CH3:8])[CH:5]=[CH:4][N:3]=1)(=[O:10])[CH3:12]Komponenten
3
Versuchsvorschrift
As a process for the preparation of 2-hydroxy-4-methylpyridine, a process whereby [iv]-4-methylpyridine is reacted with acetyl hypofluorite at −10° C. to obtain a 2-acetoxy-4-methylpyridine, and thereafter the 2-acetoxy-4-methylpyridine is hydrolyzed to obtain 4-methyl-2-pyridone is reported [Journal of the American Chemical Society, 109, 3789-3790, (1987): Non-Patent Reference 2].
Quellen und Nachweise
- ORD-Eintrag
- ord-211211d4fbe349f594fdf97b1263bdff
- Quelldatensatz
- uspto-grants-2012_07
- Patentnummer
- US08227234B2
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