Trifluoroacetic acid → HCID 178483008, Verbindung
Reaktionsgleichung
C(O)(C(F)(F)F)=O.C(O[N:13]([CH2:17][C:18]1[NH:22][C:21]2[CH:23]=[CH:24][CH:25]=[C:26]([C:27]([O:29][CH3:30])=[O:28])[C:20]=2[N:19]=1)[CH:14]=C=O)(C)(C)C>C(Cl)Cl>[CH3:14][NH:13][CH2:17][C:18]1[NH:19][C:20]2[C:26]([C:27]([O:29][CH3:30])=[O:28])=[CH:25][CH:24]=[CH:23][C:21]=2[N:22]=1Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
TFA (15 ml) was added to a cooled solution (0° C.) of methyl 2-((tert-butoxy-carbonyl(methyl)amino)methyl)-1H-benzo[d]imidazole-4-carboxylate (12.54 mmol) in methylene chloride (60 ml) and the reaction mixture was stirred at room temperature for 2 h. The solvent was evaporated off completely, in vacuo, and the residue was co-distilled 2× with methylene chloride and employed in the next stage.