Trifluoroacetic acid → tert-butyl 6-(8-(benzo[d]thiazol-2-ylcarbamoyl)-3,4-dihydroisoquinolin-2(1H)-yl)-3-(3-(2-chloropyridin-4-yloxy)propyl)picolinate

Reaktionsgleichung

C(O)(C(F)(F)F)=O.S1C2C=CC=CC=2N=C1NC(C1C=CC=C2C=1CN(C1SC(CCCOC3C=CC(C4C(C#N)=CSC=4)=CC=3)=C(C(O)=O)N=1)CC2)=O.S1C2C=CC=CC=2N=C1NC(C1C=CC=C2C=1CN(C1SC(CCCI)=C(C(OCC)=O)N=1)CC2)=O.[S:91]1[C:95]2[CH:96]=[CH:97][CH:98]=[CH:99][C:94]=2[N:93]=[C:92]1[NH:100][C:101]([C:103]1[CH:104]=[CH:105][CH:106]=[C:107]2[C:112]=1[CH2:111][N:110]([C:113]1[N:118]=[C:117]([C:119]([O:121][C:122]([CH3:125])([CH3:124])[CH3:123])=[O:120])[C:116]([CH2:126][CH2:127][CH2:128]I)=[CH:115][CH:114]=1)[CH2:109][CH2:108]2)=[O:102].[Cl:130][C:131]1[CH:136]=[C:135]([OH:137])[CH:134]=[CH:133][N:132]=1>>[S:91]1[C:95]2[CH:96]=[CH:97][CH:98]=[CH:99][C:94]=2[N:93]=[C:92]1[NH:100][C:101]([C:103]1[CH:104]=[CH:105][CH:106]=[C:107]2[C:112]=1[CH2:111][N:110]([C:113]1[N:118]=[C:117]([C:119]([O:121][C:122]([CH3:125])([CH3:124])[CH3:123])=[O:120])[C:116]([CH2:126][CH2:127][CH2:128][O:137][C:135]3[CH:134]=[CH:133][N:132]=[C:131]([Cl:130])[CH:136]=3)=[CH:115][CH:114]=1)[CH2:109][CH2:108]2)=[O:102]