Potassium Carbonate → 6-Ethynylnaphthalen-2-ol

Beteiligte Stoffe

Reaktionsschritte

Compound 110A (770 mg, 3.20 mmol) in MeOH (5 ml) and THF (10 ml) was treated with K2CO3 (885 mg, 6.41 mmol) at room temperature for 3 h. The reaction was diluted with ethyl acetate and washed with water. The organic layer was concentrated and the residue was purified by flash chromatography, eluted with DCM to provide the compound 110B.

Herkunft & Nachweise