4-Methoxy-3-methylbenzoic Acid → (r/s)-4-Methoxy-n-(5-methoxy-2,3-dihydro-1h-inden-1-yl)-3-methylbenzamide
Reaktionsgleichung
[CH3:1][O:2][C:3]1[CH:11]=[CH:10][C:6]([C:7]([OH:9])=O)=[CH:5][C:4]=1[CH3:12].[CH3:13][O:14][C:15]1[CH:16]=[C:17]2[C:21](=[CH:22][CH:23]=1)[CH:20]([NH2:24])[CH2:19][CH2:18]2>>[CH3:1][O:2][C:3]1[CH:11]=[CH:10][C:6]([C:7]([NH:24][CH:20]2[C:21]3[C:17](=[CH:16][C:15]([O:14][CH3:13])=[CH:23][CH:22]=3)[CH2:18][CH2:19]2)=[O:9])=[CH:5][C:4]=1[CH3:12]Komponenten
3
Versuchsvorschrift
Prepared in a similar manner to example 4 using 4-methoxy-3-methylbenzoic acid and 5-methoxy-2,3-dihydro-1H-inden-1-amine (Example 121-2a)(47%). MS (M+Hs 312).
Quellen und Nachweise
- ORD-Eintrag
- ord-49c629a992714aed9780acbfb44cb4cc
- Quelldatensatz
- uspto-grants-2015_07
- Patentnummer
- US09072313B2