HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-Bromobenzenethiol → 4-Hydroxy-4-(2-mercapto-phenyl)-piperidine-1-carboxylic acid tert-butyl ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-Bromobenzenethiol | HCID 80598 | — |
| Edukt | tert-Butyl 4-oxopiperidine-1-carboxylate | HCID 735900 | — |
| Edukt | 4-(5-Fluoro-2-mercapto-phenyl)-4-hydroxy-piperidine-1-carboxylic acid tert-butyl ester | HCID 68682113 | — |
| Produkt | 4-Hydroxy-4-(2-mercapto-phenyl)-piperidine-1-carboxylic acid tert-butyl ester | HCID 68682215 | — |
Reaktionsschritte
This intermediate was prepared from 2-bromo-benzenethiol and 4-oxo-piperidine-1-carboxylic acid tert-butyl ester in a similar way as described for 4-(5-fluoro-2-mercapto-phenyl)-4-hydroxy-piperidine-1-carboxylic acid tert-butyl ester.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07732463B2 |
| Quelldatensatz | uspto-grants-2010_06 |
| ORD ID | ord-b73883d285c14f8994f382c64271343a |
| Quellennotiz | uspto-grants-2010_06 |